Monthly Archives: August 2015

Forensic toxicology

The Difference Between Forensic Toxicology and Pharmacology

This article explains The Difference Between Forensic Toxicology and Pharmacology and the scientific, legal or practical evidence readers should understand.

Expert witness

An Expert Witness Analyzes Field Sobriety Tests

This article explains An Expert Witness Analyzes Field Sobriety Tests and the scientific, legal or practical evidence readers should understand.

Forensic toxicologist

A Forensic Toxicologist Examines Blood and Breath Testing

This article explains A Forensic Toxicologist Examines Blood and Breath Testing and the scientific, legal or practical evidence readers should understand.

forensic toxicologist

Why I Became a Forensic Toxicologist

This article explains Why I Became a Forensic Toxicologist and the scientific, legal or practical evidence readers should understand.

forensic toxicology

The Science Behind Forensic Toxicology

This article explains The Science Behind Forensic Toxicology and the scientific, legal or practical evidence readers should understand.

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Recent Blog Articles

Total and Unbound Drug Concentrations: What a Fasting Study Could Not Resolve

A laboratory can quantify total drug in plasma while struggling to quantify the much smaller unbound portion. That difference can determine whether a pharmacokinetic study answers its question. A result reported as not statistically significant does not resolve the question when the measurements are too limited to detect a meaningful…

Read Article: Total and Unbound Drug Concentrations: What a Fasting Study Could Not Resolve

Midazolam Sedation Models: Why a Medication Association Does Not Prove Antagonism

A medication can be associated with a different drug response because of the condition it was prescribed to treat. That possibility matters when interpreting a concentration-response model as evidence of a pharmacodynamic interaction. Franken and colleagues examined this problem in a study of midazolam sedation in terminally ill adults. Their…

Read Article: Midazolam Sedation Models: Why a Medication Association Does Not Prove Antagonism

CBD After Repeated Dosing: Why Detectability Does Not Establish a Washout Deadline

A cannabinoid detected after dosing stops is evidence of analytical persistence. It does not, by itself, establish an exact elimination half-life, the time of the last dose or a universal date when another person’s sample will test negative. A controlled study by Wolinsky and colleagues helps explain the distinction. Published…

Read Article: CBD After Repeated Dosing: Why Detectability Does Not Establish a Washout Deadline