Monthly Archives: July 2016

Analysis of Crash Risk Under the Influence of Drugs

forensic toxicology working group members July 29, 2016 Forensic Toxicology

This article explains Analysis of Crash Risk Under the Influence of Drugs and the scientific, legal or practical evidence readers should understand.

Understanding Pharmacogenetic Variability

forensic toxicology working group members July 22, 2016 Forensic Toxicology

This article explains Understanding Pharmacogenetic Variability and the scientific, legal or practical evidence readers should understand.

Discussing the Different Variables of Addiction

forensic toxicology working group members July 19, 2016 Forensic Toxicology

This article explains Discussing the Different Variables of Addiction and the scientific, legal or practical evidence readers should understand.

DUI Misdemeanor vs Felony

forensic toxicology working group members July 15, 2016 Forensic Toxicology

This article explains DUI Misdemeanor vs Felony and the scientific, legal or practical evidence readers should understand.

Understanding Pharmacokinetic Variability

forensic toxicology working group members July 12, 2016 Forensic Toxicology

This article explains Understanding Pharmacokinetic Variability and the scientific, legal or practical evidence readers should understand.

Why Having a Toxicology Expert Witness will help Your Motor Vehicle Accident Case

forensic toxicology working group members July 5, 2016 Forensic Toxicology

This article explains Why Having a Toxicology Expert Witness will help Your Motor Vehicle Accident Case and the scientific, legal or practical evidence readers should understand.

Understanding Pharmacodynamic Variability

forensic toxicology working group members July 1, 2016 Forensic Toxicology

This article explains Understanding Pharmacodynamic Variability and the scientific, legal or practical evidence readers should understand.

Recent Blog Articles

October 29, 2026

Acute THC Altered Adrenal Catecholamine Stores Without a Matching Enzyme Decline

An experimental THC study found lower adrenal-medullary catecholamine stores after acute exposure without a statistically significant decline in a key synthesis enzyme. The changes disappeared with repeated treatment, while circulating hormones followed partly different patterns. Tissue content and enzyme activity were separate measures Acute THC decreased adrenal norepinephrine and epinephrine…

Read Article: Acute THC Altered Adrenal Catecholamine Stores Without a Matching Enzyme Decline

October 29, 2026

Rimonabant Analogues Produced Cannabinoid-Like Mouse Behaviors Without THC-Like Drug Cues

Some experimental rimonabant analogues produced cannabinoid-like effects in mouse tests but did not reproduce THC's learned drug cue. Other comparisons also separated the compounds from THC, cautioning against equating a similar outward profile with the same pharmacology. Behavioral similarity was only the starting point O-6629 and O-6658 produced dose-dependent effects…

Read Article: Rimonabant Analogues Produced Cannabinoid-Like Mouse Behaviors Without THC-Like Drug Cues

October 29, 2026

Whole-Brain Receptor Assays Stayed Unchanged Despite Marked THC Behavioral Tolerance in Mice

A mouse study detected substantial THC behavioral tolerance without significant changes in whole-brain receptor binding or mRNA. The result limits a simple whole-brain explanation while leaving regional or functional changes unresolved. Behavior and biochemical assays were different endpoints Mice received THC twice daily for six and a half days. Testing…

Read Article: Whole-Brain Receptor Assays Stayed Unchanged Despite Marked THC Behavioral Tolerance in Mice