Monthly Archives: July 2016

blood testing

Analysis of Crash Risk Under the Influence of Drugs

This article explains Analysis of Crash Risk Under the Influence of Drugs and the scientific, legal or practical evidence readers should understand.

okorie okorocha

Understanding Pharmacogenetic Variability

This article explains Understanding Pharmacogenetic Variability and the scientific, legal or practical evidence readers should understand.

expert witness

Discussing the Different Variables of Addiction

This article explains Discussing the Different Variables of Addiction and the scientific, legal or practical evidence readers should understand.

alcohol testing

DUI Misdemeanor vs Felony

This article explains DUI Misdemeanor vs Felony and the scientific, legal or practical evidence readers should understand.

toxicology lawyer

Understanding Pharmacokinetic Variability

This article explains Understanding Pharmacokinetic Variability and the scientific, legal or practical evidence readers should understand.

toxicology-co-counsel

Why Having a Toxicology Expert Witness will help Your Motor Vehicle Accident Case

This article explains Why Having a Toxicology Expert Witness will help Your Motor Vehicle Accident Case and the scientific, legal or practical evidence readers should understand.

Forensic lawyers

Understanding Pharmacodynamic Variability

This article explains Understanding Pharmacodynamic Variability and the scientific, legal or practical evidence readers should understand.

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Recent Blog Articles

Total and Unbound Drug Concentrations: What a Fasting Study Could Not Resolve

A laboratory can quantify total drug in plasma while struggling to quantify the much smaller unbound portion. That difference can determine whether a pharmacokinetic study answers its question. A result reported as not statistically significant does not resolve the question when the measurements are too limited to detect a meaningful…

Read Article: Total and Unbound Drug Concentrations: What a Fasting Study Could Not Resolve

Midazolam Sedation Models: Why a Medication Association Does Not Prove Antagonism

A medication can be associated with a different drug response because of the condition it was prescribed to treat. That possibility matters when interpreting a concentration-response model as evidence of a pharmacodynamic interaction. Franken and colleagues examined this problem in a study of midazolam sedation in terminally ill adults. Their…

Read Article: Midazolam Sedation Models: Why a Medication Association Does Not Prove Antagonism

CBD After Repeated Dosing: Why Detectability Does Not Establish a Washout Deadline

A cannabinoid detected after dosing stops is evidence of analytical persistence. It does not, by itself, establish an exact elimination half-life, the time of the last dose or a universal date when another person’s sample will test negative. A controlled study by Wolinsky and colleagues helps explain the distinction. Published…

Read Article: CBD After Repeated Dosing: Why Detectability Does Not Establish a Washout Deadline