DRE Agreement With Any Drug Administration Differed From Correct Drug-Class Identification

In a laboratory DEC study, agreement with administration of any active drug was a different endpoint from correctly identifying the drug class. The reported percentages should not be merged into one cannabis-impairment accuracy claim.

The study compared several drug conditions

Heishman, Singleton and Crouch studied 48 volunteers in a double-blind laboratory experiment involving alprazolam, d-amphetamine, codeine and marijuana. The study examined drug-evaluation observations and officers’ opinions against controlled administration and toxicology.

Across the studied drug conditions, 76% of opinions about impairment were consistent with administration of an active drug. Drug-class opinions were consistent with toxicology under the stated classification standards in 32% of cases. Those figures had different targets.

A broader target is easier to satisfy

An opinion can agree that some active drug was administered while naming the wrong category. That outcome counts differently when the question is any drug versus the particular class. The denominator and scoring rule are therefore essential to any percentage.

These were pooled results across multiple drugs. Neither 76% nor 32% should be quoted as marijuana-specific sensitivity or as the probability that a cannabis-positive driver was functionally impaired.

Controlled administration was not a driving reference

Knowing which drug was given is valuable experimental information, but it is not the same reference as independently measured driving performance. The timing of examinations relative to drug effects also matters; the report identified marijuana as an exception to its near-maximum plasma scheduling.

For a useful interpretation, state the target explicitly: administration, toxicological detection, drug category or performance. The study’s main lesson here is how much an apparent accuracy figure can change when the endpoint changes, even within one experiment.

Related: How the reference specimen changes a cannabis accuracy claim.

Research cited

Heishman SJ; Singleton EG; Crouch DJ; Journal of Analytical Toxicology; 1998. Laboratory Validation Study of Drug Evaluation and Classification Program: Alprazolam, d-Amphetamine, Codeine, and Marijuana.

Spread the love


The National Black Lawyers

top 40 lawyers

civil trial law

Lawyers of Distinction

Loading...

Recent Blog Articles

Oral THCA-A Exposure Did Not Produce Detectable Hair THCA-A in One Volunteer

In a small controlled experiment, one volunteer took oral THCA-A repeatedly without producing detectable THCA-A in the sampled hair or sebum/sweat. That finding questions a simple assumption that systemic exposure necessarily yields a positive hair result for the same cannabinoid. This experiment tested the plant acid Moosmann and colleagues reported…

Spread the love

Read Article: Oral THCA-A Exposure Did Not Produce Detectable Hair THCA-A in One Volunteer

CB2 Effects on Established Neuropathy Did Not Establish Prevention of Its Onset

An experimental CB2 agonist could reduce hypersensitivity after neuropathy was established while only delaying its development under another treatment schedule. A mouse study illustrates why treatment of an existing response and prevention of its onset need separate evidence. The experiments asked different timing questions The supplied Guenther and colleagues preprint…

Spread the love

Read Article: CB2 Effects on Established Neuropathy Did Not Establish Prevention of Its Onset

A CB1 Modulator Changed Colonic Transit Without Changing Fecal Output

An experimental cannabinoid-receptor modulator reduced morphine-induced slowing of colonic transit without changing fecal boli production in the reported experiment. Those outcomes are related, but they are not interchangeable measures of gastrointestinal benefit. The compound was not cannabis The supplied Iyer and colleagues preprint examined GAT358, a negative allosteric modulator of…

Spread the love

Read Article: A CB1 Modulator Changed Colonic Transit Without Changing Fecal Output

Speak with an expert today!

Contact the offices of Okorie Okorocha for professional and reliable advice which you can trust.

Call (424) 363-3347 Contact Us