The Journey of The Drug Test

Toxicology Student Submissions December 9, 2016 Forensic Toxicology

Article overview: This article explains Telling History with Hair and the scientific, legal or practical evidence readers should understand.

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How a drug test moves from collection to interpretation

What Forensic Toxicology can Learn from Hair You’re probably aware that most of your hair is ‘dead’. Only the follicle below the skin is alive – this is the part used for DNA testing in other forensic fields. In forensic toxicology, however, the dead part of the hair can reveal a wealth of information. In fact, by analyzing your hair, a forensic toxicologist can recreate the history of your interactions with chemicals, drugs and toxins. Why Analyze Hair? Hair has no active metabolism because it isn’t alive. As it grows, substances from the bloodstream are deposited in the strand via the follicle, with no means of removing them. Your organs, on the other hand, will process toxins in your body and eliminate them over time. Thus blood, urine, and saliva have relatively short windows of detection – usually between a few hours to a few days, depending on the sample. Because hair grows fairly slowly and consistently (about half an inch every month), each strand essentially captures a chemical timeline of the subject in question. In other words, a forensic toxicologist can segment the strand of hair and examine what chemicals or toxins were present in the subject across a longer period of time. Depending on the length of the hair, the window of detection can range from a few months to a year. Forensic hair analysis is a non-invasive means of testing living subjects. But is also useful for recreating a toxicology timeline in cases where the cause of death is disputed. Hair analysis can even be carried out on exhumed or partially decomposed bodies, where other fluid or tissue samples are too thoroughly degraded. How It Works Ideally, a hair sample is taken from the back of the head or close to the skin. It should be decontaminated in the lab, and stripped of any external materials that may interfere with the testing. In most cases, an initial immunoassay test screens for the possible presence of drugs or toxins. Then a more rigorous analysis – typically gas chromatography or mass spectrometry – must be carried out to confirm the findings, and determine the specific chemicals in the sample. Applications for Hair Analysis

Hair analysis is very useful for drug testing, especially when looking at long-term usage. It’s often used to test for the presence of marijuana, cocaine, amphetamines, and heroin. It may even be able to detect chronic alcohol abuse. Private companies may use hair analysis to test employees for drug use, although urine remains the most common sample for this.
Courts may also order screenings of hair in child custody cases, to determine if children were exposed to drugs by their parents.
Hair can reveal exposure to dangerous chemicals and heavy metals, as in the case of environmental poisoning. In a class action lawsuit, for example, hair samples from multiple subjects can indicate the presence of illegal toxins in their everyday environment.
Hair analysis can be used to determine if someone was drugged – especially useful in cases of ‘date rape’.

Advantages and Disadvantages On the one hand, hair analysis gives a broad and thorough history of a subject’s toxicology, due to its large window of detection. It is non-invasive (unlike taking a blood sample), and it’s almost impossible to fake a hair sample, as the analyst can collect the sample themselves (unlike a urine sample). On the other hand, surface materials – like hair dye or bleach – may contaminate a sample, invalidating any findings. Similarly, prescription drugs or birth control may also alter findings. For thorough analysis, multiple hair samples should be tested, or used in conjunction with other methods of examination.